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XRCC4 rabbit pAb

CAT: 0855-ES3716-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3716-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D) J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED) . Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015]
Description
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],
Product Name Alternative
XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4
UniProt
Q13426
Swiss Prot
Q13426
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human XRCC4. AA range:261-310
Target
XRCC4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
40kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
40kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome . Localizes to site of double-strand breaks. .; [Protein XRCC4, C-terminus]: Cytoplasm . Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3) . .
Other Product Names
XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4
Gene ID (Human)
7518

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