XRCC4 rabbit pAb
CAT:
855-ES3716-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
XRCC4 rabbit pAb
- Description: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V (D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],
- Synonyms: XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4
- Gene ID: 7518
- UniProt: Q13426
- Cellular Locus: Nucleus. Chromosome. Localizes to site of double-strand breaks..; [Protein XRCC4, C-terminus]: Cytoplasm. Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3)..
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: The antiserum was produced against synthesized peptide derived from human XRCC4. AA range:261-310
- Clonality: Polyclonal
- Validated Applications: WB, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
- Molecular Weight: 40kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.