ATG14L Rabbit rabbit pAb

• Background:

  Miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.

• Description:

  Miscellaneous: The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.

• UniProt:

  Q6ZNE5

• Swiss Prot:

  Q6ZNE5

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Protein of ATG14L

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF

• Concentration:

  1 mg/ml

• Dilution:

  IHC-p 1:50-300

• Molecular Weight:

  55kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  55kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Preautophagosomal structure membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Cytosolic under nutrient-rich conditions (PubMed:19050071) . Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071) . Accumulates on highly curved PtdIns (3) P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity) . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity) . .

• Other Product Names:

  Beclin 1-associated autophagy-related key regulator (Barkor; Autophagy-related protein 14-like protein; Atg14L)

• Gene ID (Human):

  22863