ATG14L Rabbit rabbit pAb

ATG14L Rabbit rabbit pAb

• Description: Miscellaneous: The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.
• Synonyms: Beclin 1-associated autophagy-related key regulator (Barkor;Autophagy-related protein 14-like protein;Atg14L)
• Gene ID: 22863
• UniProt: Q6ZNE5
• Cellular Locus: Cytoplasm. Endoplasmic reticulum membrane ; Peripheral membrane protein. Preautophagosomal structure membrane ; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein. Cytosolic under nutrient-rich conditions (PubMed:19050071). Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071). Accumulates on highly curved PtdIns(3)P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity)..
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant Protein of ATG14L
• Clonality: Polyclonal
• Validated Applications: IHC, IF
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: IHC-p 1:50-300
• Molecular Weight: 55kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.