Products for Research Use Only
RegisterLogin

WNK1 rabbit pAb

CAT: 0855-ES3705-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES3705-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]
Description
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined. [provided by RefSeq, May 2010],
UniProt
Q9H4A3
Swiss Prot
Q9H4A3
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human WNK1. AA range:24-73
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
230kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
230kD
Fragment
IgG
Subcellular Location
Cytoplasm .
Other Product Names
WNK1; HSN2; KDP; KIAA0344; PRKWNK1; Serine/threonine-protein kinase WNK1; Erythrocyte 65 kDa protein; p65; Kinase deficient protein; Protein kinase lysine-deficient 1; Protein kinase with no lysine 1; hWNK1
Gene ID (Human)
65125

UniProtKB · Q9H4A3

Serine/threonine-protein kinase WNK1

WNK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H4A3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WNK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A1L4B0, C5HTZ5, C5HTZ6, C5HTZ7, H6WZW3, O15052, P54963, Q4VBX9, Q6IFS5, Q86WL5, Q8N673, Q96CZ6, Q9P1S9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Ligand

ATP-bindingChlorideNucleotide-binding

Cellular component

CytoplasmCytoskeletonNucleus

PTM

GlycoproteinPhosphoproteinUbl conjugation

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

Disease

NeurodegenerationNeuropathy

Related Products

CatalogName
ES1482-01WNK1 (phospho Thr60) rabbit pAb
ES10219-01WNK3 rabbit pAb
ES9109-01WNK2 rabbit pAb
ES10220-01WNK4 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb

Alternative Products

CatalogName
MBS8560029-01WNK1 Rabbit pAb
RDSA67706WNK1 Rabbit mAb
GTR18219259-01Rabbit WNK1 Antibody

Popular Products