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THC2 rabbit pAb

CAT: 0855-ES3604-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3604-02Size:100 µL
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Background
This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Feb 2010]
Description
This gene encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Feb 2010],
UniProt
Q96GX5
Swiss Prot
Q96GX5
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MASTL. AA range:821-870
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
97kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
97kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus . Cleavage furrow . During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes. Upon mitotic exit moves to the cleavage furrow. .
Other Product Names
MASTL; GW; GWL; THC2; Serine/threonine-protein kinase greatwall; GW; GWL; hGWL; Microtubule-associated serine/threonine-protein kinase-like; MAST-L
Gene ID (Human)
84930

UniProtKB · Q96GX5

Serine/threonine-protein kinase greatwall

GWL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96GX5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MASTL
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GW, GWL, hGWL
EC number
2.7.11.1
Processing
—
Secondary accessions
Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell cycleCell divisionMitosis

Cellular component

CytoplasmCytoskeletonNucleus

Disease

Disease variant

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

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