ST18 rabbit pAb

• Background:

  Function:Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity) . Inhibits colony formation in cultured breast cancer cells., similarity:Contains 6 C2HC-type zinc fingers., tissue specificity:Detected at low levels in heart, liver, kidney, skeletal muscel, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells.

• Description:

  Function: Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells. similarity: Contains 6 C2HC-type zinc fingers. tissue specificity: Detected at low levels in heart, liver, kidney, skeletal muscel, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells.

• Synonyms:

  ST18; KIAA0535; ZNF387; Suppression of tumorigenicity 18 protein; Zinc finger protein 387

• Gene ID:

  9705

• UniProt:

  O60284

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human ZNF387. AA range:41-90

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  115kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  115 kD

• Subcellular Location:

  Nucleus .

• Other Product Names:

  ST18; KIAA0535; ZNF387; Suppression of tumorigenicity 18 protein; Zinc finger protein 387

• Gene ID (Human):

  9705

• SwissProt (Human):

  O60284