Scn4b rabbit pAb

• Background:

  The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10) . Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009]

• Description:

  The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene. [provided by RefSeq, Mar 2009],

• Synonyms:

  SCN4B; Sodium channel subunit beta-4

• Gene ID:

  6330

• UniProt:

  Q8IWT1

• Cellular Locus:

  Cell membrane ; Single-pass type I membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human SCN4B. AA range:61-110

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  27kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  27 kD

• Subcellular Location:

  Cell membrane ; Single-pass type I membrane protein .

• Other Product Names:

  SCN4B; Sodium channel subunit beta-4

• Gene ID (Human):

  6330

• SwissProt (Human):

  Q8IWT1