RBAK rabbit pAb

• Background :

  This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]

• Description :

  This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011],

• UniProt :

  Q9NYW8

• Swiss Prot :

  Q9NYW8

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human RBAK. AA range:1-50

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IF; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IF/ICC 1:50-200; ELISA 1:2000-20000; IHC-p 1:50-200

• Molecular Weight :

  85kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  85kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus .

• Other Product Names :

  RBAK; ZNF769; RB-associated KRAB zinc finger protein; RB-associated KRAB repressor; hRBaK; Zinc finger protein 769

• Gene ID (Human) :

  57786