RBAK rabbit pAb

CAT: 0855-ES3334-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES3334-01Size:50 µL
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Background
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]
Description
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011],
UniProt
Q9NYW8
Swiss Prot
Q9NYW8
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RBAK. AA range:1-50
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IF/ICC 1:50-200; ELISA 1:2000-20000; IHC-p 1:50-200
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
RBAK; ZNF769; RB-associated KRAB zinc finger protein; RB-associated KRAB repressor; hRBaK; Zinc finger protein 769
Gene ID (Human)
57786

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