PSCA rabbit pAb

• Background :

  This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

• Description :

  This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],

• UniProt :

  O43653

• Swiss Prot :

  O43653

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human Prostate Stem Cell Antigen. AA range:41-90

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Molecular Weight :

  29kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  29kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Lipid-anchor, GPI-anchor .

• Other Product Names :

  PSCA; Prostate stem cell antigen

• Gene ID (Human) :

  8000