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PICln rabbit pAb

CAT: 0855-ES3206-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3206-01Size:50 µL
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Background
This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Description
This gene encodes a protein that functions in multiple regulatory pathways. The encoded protein complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. The protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of this gene are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015],
Product Name Alternative
CLNS1A; CLCI; ICLN; Methylosome subunit pICln; Chloride channel; nucleotide sensitive 1A; Chloride conductance regulatory protein ICln; I (Cln) ; Chloride ion current inducer protein; ClCI; Reticulocyte pICln
UniProt
P54105
Swiss Prot
P54105
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CLNS1A. AA range:184-233
Target
PICln
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
37kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
37kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol . Nucleus . Cytoplasm, cytoskeleton . A small fraction is also associated with the cytoskeleton (PubMed:18984161) .
Other Product Names
CLNS1A; CLCI; ICLN; Methylosome subunit pICln; Chloride channel; nucleotide sensitive 1A; Chloride conductance regulatory protein ICln; I (Cln) ; Chloride ion current inducer protein; ClCI; Reticulocyte pICln
Gene ID (Human)
1207

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