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JIK rabbit pAb

CAT: 0855-ES2658-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2658-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF) . When overexpressed, may activate ERK1/ERK2 and JNK/SAPK., PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., subcellular location:Also localized to the peripheral cell membrane., subunit:Self-associates., tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Description
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK. PTM: Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. similarity: Contains 1 protein kinase domain. subcellular location: Also localized to the peripheral cell membrane. subunit: Self-associates. tissue specificity: Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Product Name Alternative
TAOK3; DPK; JIK; KDS; MAP3K18; Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhi
UniProt
Q9H2K8
Swiss Prot
Q9H2K8
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TAOK3. AA range:531-580
Target
JIK
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
110kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
110kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell membrane ; Peripheral membrane protein . Also localized to the peripheral cell membrane.
Other Product Names
TAOK3; DPK; JIK; KDS; MAP3K18; Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhi
Gene ID (Human)
51347

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