GBDR1 rabbit pAb

• Background :

  Function:Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 STI1 domain., similarity:Contains 1 ubiquitin-like domain., similarity:Contains 2 UBA domains., subunit:Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain., tissue specificity:Ubiquitous.

• Description :

  Function: Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. pathway: Protein modification; protein ubiquitination. similarity: Contains 1 STI1 domain. similarity: Contains 1 ubiquitin-like domain. similarity: Contains 2 UBA domains. subunit: Component of the KPC complex composed of RNF123/KPC1 and UBAC1/KPC2. Interacts with RNF123 via its N-terminal domain. Interacts with the proteasome via its N-terminal domain. tissue specificity: Ubiquitous.

• UniProt :

  Q9BSL1

• Swiss Prot :

  Q9BSL1

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human UBAC1. AA range:91-140

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  45kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  45kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm .

• Other Product Names :

  UBAC1; GBDR1; KPC2; UBADC1; Ubiquitin-associated domain-containing protein 1; UBA domain-containing protein 1; E3 ubiquitin-protein ligase subunit KPC2; Glialblastoma cell differentiation-related protein 1; Kip1 ubiquitination-promoting com

• Gene ID (Human) :

  10422