RegisterLogin

E2F-2 rabbit pAb

CAT: 0855-ES2212-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES2212-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits
Description
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits
UniProt
Q14209
Swiss Prot
Q14209
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human E2F2. AA range:221-270
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
E2F2; Transcription factor E2F2; E2F-2
Gene ID (Human)
1870

Related Products

CatalogName
ES20062-01E2F-2 (Acetyl Lys122) rabbit pAb
ES8529-01E2F-1 rabbit pAb
ES5038-01E2F-5 rabbit pAb
ES4052-01E2F-4 rabbit pAb
ES2214-01E2F-6 rabbit pAb
ES2213-01E2F-4/5 rabbit pAb
ES1100-01E2F-4 (Acetyl Lys96) rabbit pAb
ES8820-01E2F-1 (Acetyl-K117) rabbit pAb
ES5036-01E2F-1 (phospho Thr433) rabbit pAb
ES8446-01E2F-1 (Acetyl Lys120) rabbit pAb

Alternative Products

CatalogName
H00001870-D01PRabbit Polyclonal E2F-2 Antibody
E53P03627E2F-2 Rabbit Polyclonal Antibody
MBS8597434-01E2F-2 (Acetyl Lys122) rabbit pAb
NBP3-16165-20ulRabbit Monoclonal E2F-2 Antibody (1H7D6)
BT-AP09397-01E2F-2 (Acetyl Lys122) Rabbit Polyclonal Antibody
E46F1947E2F transcription factor 2 Rabbit Monoclonal Antibody
MBS9518294-01E2F-2 (Acetyl-Lys122) Rabbit Polyclonal Antibody
MBS077694Rabbit E2F Transcription Factor 2 ELISA Kit
E2251436E2F-4 Rabbit pAb
MBS8541878-01E2F-1 Rabbit pAb

Popular Products