RegisterLogin

E2F-4/5 rabbit pAb

CAT: 0855-ES2213-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES2213-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated ge
Description
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated ge
UniProt
Q16254/Q15329
Swiss Prot
Q16254/Q15329
Reactivity
Human; Mouse; Rat; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human E2F4. AA range:51-100
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
44kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
44kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
E2F4; Transcription factor E2F4; E2F-4; E2F5; Transcription factor E2F5; E2F-5
Gene ID (Human)
1874/1875

Related Products

CatalogName
ES5038-01E2F-5 rabbit pAb
ES4052-01E2F-4 rabbit pAb
ES1100-01E2F-4 (Acetyl Lys96) rabbit pAb
ES2212-01E2F-2 rabbit pAb
ES8529-01E2F-1 rabbit pAb
ES2214-01E2F-6 rabbit pAb
ES8820-01E2F-1 (Acetyl-K117) rabbit pAb
ES5036-01E2F-1 (phospho Thr433) rabbit pAb
ES20062-01E2F-2 (Acetyl Lys122) rabbit pAb
ES8446-01E2F-1 (Acetyl Lys120) rabbit pAb

Alternative Products

CatalogName
E28PT1444E2F-4/5 Rabbit Polyclonal Antibody
E2251436E2F-4 Rabbit pAb
PAV6813Rabbit Anti-E2F-4/5/E2F4 Polyclonal Antibody
E28PT1445E2F-5 Rabbit Polyclonal Antibody
NBP2-98787-50ulRabbit Polyclonal E2F-4 Antibody
APRab10255-01E2F-4 Rabbit Polyclonal Antibody
MBS460275-01Rabbit anti E2F-5 Polyclonal Antibody
NBP3-15850-100ulRabbit Monoclonal E2F-4 Antibody (3O6Y9)
NBP1-21374FRabbit Polyclonal E2F-4 Antibody [FITC]
NBP2-98787APCRabbit Polyclonal E2F-4 Antibody [Allophycocyanin]

Popular Products