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E2F-5 rabbit pAb

CAT:
855-ES5038-01
Size:
50 μL
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
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E2F-5 rabbit pAb

  • Description: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 inter
  • Synonyms: E2F5; Transcription factor E2F5; E2F-5
  • Gene ID: 1875
  • UniProt: Q15329
  • Cellular Locus: Nucleus.
  • Host: Rabbit
  • Species Reactivity: Human, Mouse, Rat
  • Immunogen: The antiserum was produced against synthesized peptide derived from human E2F-5. AA range:93-142
  • Clonality: Polyclonal
  • Validated Applications: WB, ELISA
  • Stability: 1 year
  • Concentration: 1 mg/mL
  • Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Molecular Weight: 36kD
  • Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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