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BRAF35 rabbit pAb

CAT: 0855-ES1786-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1786-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters., sequence caution:Translation N-terminally extended., similarity:Contains 1 HMG box DNA-binding domain., subcellular location:Localized to condensed chromosomes in mitosis in conjunction with BRCA2., subunit:Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein., tissue specificity:Ubiquitously expressed in adult tissues.
Description
Function: Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters. sequence Caution: Translation N-terminally extended. similarity: Contains 1 HMG box DNA-binding domain. subcellular location: Localized to condensed chromosomes in mitosis in conjunction with BRCA2. subunit: Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein. tissue specificity: Ubiquitously expressed in adult tissues.
UniProt
Q9P0W2
Swiss Prot
Q9P0W2
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human HMG20B. AA range:1-50
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
36kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
36kD
Fragment
IgG
Subcellular Location
Nucleus. Chromosome. Localized to condensed chromosomes in mitosis in conjunction with BRCA2.
Other Product Names
HMG20B; BRAF35; HMGX2; HMGXB2; SMARCE1R; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SMARCE1-related protein; BRCA2-associated factor 35; HMG box-containing protein 20B; HMG domain-
Gene ID (Human)
10362

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