Products for Research Use Only
RegisterLogin

BID rabbit pAb

CAT: 0855-ES1769-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES1769-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) ; CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Description
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers Cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008],
UniProt
P55957
Swiss Prot
P55957
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human BID. AA range:44-93
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
25kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
25kD
Fragment
IgG
Subcellular Location
Cytoplasm . Mitochondrion membrane . Mitochondrion outer membrane . When uncleaved, it is predominantly cytoplasmic. .; [BH3-interacting domain death agonist p15]: Mitochondrion membrane . Translocates to mitochondria as an integral membrane protein. .; [BH3-interacting domain death agonist p13]: Mitochondrion membrane . Associated with the mitochondrial membrane. .; [Isoform 1]: Cytoplasm .; [Isoform 3]: Cytoplasm .; [Isoform 2]: Mitochondrion membrane . A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively. .
Other Product Names
BID; BH3-interacting domain death agonist; p22 BID; BID
Gene ID (Human)
637

Related Products

CatalogName
ES7131-01BID (phospho Ser78) rabbit pAb
ES19950-01BID (Cleaved-Arg71) rabbit pAb
ES19951-01BID (p11, Cleaved-Ser100) rabbit pAb
ES1012-01BID Rabbit Polyclonal Antibody
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb

Alternative Products

CatalogName
RTR015Rabbit-to-Rabbit Blocking Reagent
AR05252PU-NRabbit IgG Rabbit Protein
AR05110PU-NRabbit IgM Rabbit Protein
NBP1-71681Rabbit Normal Rabbit Serum
OORA00605-100MLRabbit
KA2017Rabbit Rabbit IgG ELISA Kit
MBS9512780-01JAK2 Rabbit Rabbit Polyclonal Antibody
MBS9512768-01VEGF Rabbit Rabbit Polyclonal Antibody
MBS9518120-01ATG4c Rabbit Rabbit Polyclonal Antibody
MBS9518118-01ATG4a Rabbit Rabbit Polyclonal Antibody

Popular Products