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AZI1 rabbit pAb

CAT: 0855-ES1739-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1739-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data., function:May play a role in spermatogenesis., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 IQ domain.
Description
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. function: May play a role in spermatogenesis. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 IQ domain.
UniProt
Q9UPN4
Swiss Prot
Q9UPN4
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human AZI1. AA range:311-360
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
130kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
130kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body. Cytoplasmic vesicle, secretory vesicle, acrosome . Colocalized with pericentriolar material protein PCM1 at centriolar satellites. During spermiogenesis, becomes enriched with nephrocystin NPHP1 at the transition zone, a structure at the base of the ciliary axoneme important for regulating traffic into the ciliary compartment. Traffics towards and away from the centrosome/basal body and the transition zone of the ciliary axoneme in a microtubule-dependent manner. Localized at the Golgi-derived acrosome and the
Other Product Names
AZI1; CEP131; KIAA1118; 5-azacytidine-induced protein 1; Centrosomal protein of 131 kDa; Cep131; Pre-acrosome localization protein 1
Gene ID (Human)
22994

UniProtKB · Q9UPN4

Centrosomal protein of 131 kDa

CP131_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UPN4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CEP131
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NHI8, B2RN11, Q96F50
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCilium biogenesis/degradationDifferentiationSpermatogenesisTransport

Cellular component

Cell projectionCytoplasmCytoplasmic vesicleCytoskeleton

Molecular function

Developmental protein

PTM

PhosphoproteinUbl conjugation

Technical term

Proteomics identificationReference proteome

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