APHC rabbit pAb

• Background :

  Enzyme regulation:Activated by Ca (2+) and inhibited by Zn (2+) ., function:Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity., similarity:Belongs to the alkaline ceramidase family., tissue specificity:Ubiquitously expressed. Highest expression in placenta.

• Description :

  Enzyme regulation: Activated by Ca (2+) and inhibited by Zn (2+). function: Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity. similarity: Belongs to the alkaline ceramidase family. tissue specificity: Ubiquitously expressed. Highest expression in placenta.

• UniProt :

  Q9NUN7

• Swiss Prot :

  Q9NUN7

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human PHCA. AA range:171-220

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight :

  35kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  35kD

• Fragment :

  IgG

• Subcellular Location :

  Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .

• Other Product Names :

  ACER3; APHC; PHCA; Alkaline ceramidase 3; AlkCDase 3; Alkaline CDase 3; Alkaline dihydroceramidase SB89; Alkaline phytoceramidase; aPHC

• Gene ID (Human) :

  55331