APC5 rabbit pAb

CAT: 0855-ES1676-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES1676-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
Description
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008],
Product Name Alternative
ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
UniProt
Q9UJX4
Swiss Prot
Q9UJX4
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200
Target
APC5
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm, cytoskeleton, spindle .
Other Product Names
ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
Gene ID (Human)
51433

Related Products

CatalogName
ES18300-01APC15 rabbit pAb
ES7194-01APC1 rabbit pAb
ES10743-01APC4 rabbit pAb
ES7193-01APC1 rabbit pAb
ES1674-01APC rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES7191-01APC1 (phospho Ser355) rabbit pAb
ES7192-01APC1 (phospho Ser688) rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb

Alternative Products

CatalogName
E47R7778APC5 Rabbit pAb
NBP3-38385-100ulRabbit Polyclonal Apc5 Antibody
E53P02052APC5 Rabbit Polyclonal Antibody
SL7778R-01Rabbit Anti-APC5 antibody
TA349477Apc5 (ANAPC5) Rabbit Polyclonal Antibody
NB100-55319APCRabbit Polyclonal Apc5 Antibody [Allophycocyanin]
NBP1-77154HRabbit Polyclonal Apc5 Antibody [HRP]
NB100-55319BRabbit Polyclonal Apc5 Antibody [Biotin]
NB100-55319PERabbit Polyclonal Apc5 Antibody [PE]
NBP1-77154PCPRabbit Polyclonal Apc5 Antibody [PerCP]

Popular Products