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APC1 (phospho Ser688) rabbit pAb

CAT: 0855-ES7192-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7192-01Size:50 µL
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Background
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
Description
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011],
UniProt
Q9H1A4
Swiss Prot
Q9H1A4
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human APC1 around the phosphorylation site of Ser688. AA range:654-703
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleoplasm, anaphase-promoting complex, cytosol
Other Product Names
ANAPC1; TSG24; Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein
Gene ID (Human)
64682

UniProtKB · Q9H1A4

Anaphase-promoting complex subunit 1

APC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H1A4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ANAPC1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
APC1
EC number
—
Processing
—
Secondary accessions
Q2M3H8, Q9BSE6, Q9H8D0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Cell cycleCell divisionMitosisUbl conjugation pathway

Disease

DwarfismEctodermal dysplasiaHypotrichosis

PTM

Phosphoprotein

Domain

Repeat

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