WIPI2 Rabbit pAb

• Background:

  WIPI2 is the mammalian homolog of Atg18, not Atg21, along with the closely related protein, WIPI1. WD40 repeat proteins regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids.

• Description:

  WIPI2 is the mammalian homolog of Atg18, not Atg21, along with the closely related protein,  WIPI1. WD40 repeat proteins regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids.

• Synonyms:

  ATG21, CGI50

• Gene ID:

  26100

• UniProt:

  Q9Y4P8

• Cellular Locus:

  Membrane

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant Protein

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC

• Validated Applications:

  IHC

• Stability:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:100-200

• Molecular Weight:

  49kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  49 kDa

• Subcellular Location:

  Membrane

• Other Product Names:

  ATG21, CGI50

• Gene ID (Human):

  26100

• SwissProt (Human):

  Q9Y4P8