WIPI2 (phospho-Ser413) rabbit pAb

WIPI2 (phospho-Ser413) rabbit pAb

• Description: WD repeat domain, phosphoinositide interacting 2 (WIPI2) Homo sapiens WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al. 2004 [PubMed 15602573]). [supplied by OMIM, Mar 2008],
• Synonyms: WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2) (WIPI49-like protein 2)
• Gene ID: 26100
• UniProt: Q9Y4P8
• Cellular Locus: Preautophagosomal structure membrane ; Peripheral membrane protein ; Cytoplasmic side. Localizes to omegasomes membranes which are endoplasmic reticulum connected structures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P..
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthesized phosho peptide around human WIPI2 (Ser413)
• Clonality: Polyclonal
• Validated Applications: WB
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:1000-2000
• Molecular Weight: 49kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.