EIF4A1 Mouse mAb

• Background:

  The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA – this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.

• Description:

  The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA – this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.

• UniProt:

  P60842

• Swiss Prot:

  P60842

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthetic Peptide

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB, IHC, IF

• Concentration:

  1mg/mL

• Dilution:

  WB 1:1,000-3,000 IF 1:100-200 IHC 1:100-200

• Molecular Weight:

  48kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  48kDa

• Fragment:

  IgG1

• Subcellular Location:

  Cytosol, Extracellular region or secreted

• Other Product Names:

  DDX2, eIF 4A I, Eukaryotic initiation factor 4A-1, ATP-dependent RNA helicase eIF4A-1, DDX2A

• Gene ID (Human):

  1973