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AMACR/P504S Mouse mAb

CAT: 0855-EM1047-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-EM1047-01Size:50 µL
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Background
AMACR has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
Description
AMACR has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
Product Name Alternative
Alpha-Methylacyl Coenzyme A Racemase ; RACE; 2-methylacyl-CoA racemase
UniProt
Q9UHK6
Swiss Prot
Q9UHK6
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC
Concentration
1mg/mL
Dilution
WB 1:1,000 IHC 1:200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
42kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
42kDa
Fragment
IgG1
Subcellular Location
Peroxisome. Mitochondrion
Other Product Names
Alpha-Methylacyl Coenzyme A Racemase ; RACE; 2-methylacyl-CoA racemase
Gene ID (Human)
23600

UniProtKB · Q9UHK6

Alpha-methylacyl-CoA racemase

AMACR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UHK6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
AMACR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
5.1.99.4
Processing
—
Secondary accessions
A5YM47, B8Y916, B8Y918, F8W9N1, O43673, Q3KT79, Q96GH1, Q9Y3Q1
Protein keywords

PTM

Acetylation

Coding sequence diversity

Alternative splicing

Disease

Disease variantIntrahepatic cholestasis

Molecular function

Isomerase

Cellular component

MitochondrionPeroxisome

Technical term

Proteomics identificationReference proteome