CAY10602

CAT: 0026-B2914-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B2914-25Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAY10602 is an activator of SIRT1. The sirtuins (SIRTs) are NAD+-dependent histone deacetylases. SIRT1 alters gene expression by deacetylating transcription factors such as NF-κB, p53, and FOXO. CAY10602 suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells at 20 μM and 60 μM. It is more potent as a suppressor of TNF-α release than resveratrol.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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