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CAY10505

CAT: 0026-B2962-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-B2962-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAY10505 is a potent inhibitor of phosphoinositide 3-kinase (PI3K), selectively inhibiting the γ isoform with an IC₅₀ of 30 nM. It inhibits the α, β, and δ isoforms of PI3K with IC₅₀ values of 0.94, 20, and 20 μM, respectively. It significantly inhibits the unrelated casein kinase 2 (CK2) with an IC₅₀ of 20 nM. It also inhibits the phosphorylation of the PI3K substrate PKB/Akt in mouse macrophages with an IC₅₀ of 228 nM. It improves hypertension-associated vascular endothelial dysfunction in rats.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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MBS3600821-01CAY10505
A11196-25CAY10505 25mg
A11196-10CAY10505 10mg
A11196-100CAY10505 100mg
A11196-50CAY10505 50mg
A11196-200CAY10505 200mg
A11196-500CAY10505 500mg
A11196-10mM-DCAY10505 10mM * 1mL in DMSO

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