L-α-Hydroxyglutaric Acid Disodium Salt
CAT:
26-B2812-5
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

L-α-Hydroxyglutaric Acid Disodium Salt
- Description: L-α-Hydroxyglutaric Acid is metabolized to 2-oxoglutarate or α-ketoglutarate by L-2-hydroxyglutarate dehydrogenase. Rare defects in L-2-hydroxyglutarate dehydrogenase cause a neurometabolic disorder characterized by 2-hydroxyglutaric aciduria. High concentrations of L-α-Hydroxyglutaric Acid inhibit histone lysine demethylases, which might promote oncogenesis. 2-hydroxyglutarate can be used in the collection buffer to improve HIF-1α recovery from tumor specimens.
- Shipping Conditions: RT
- Storage Conditions: -20ºC
- Shelf Life: 36 months