Chemerin-9, mouse

Chemerin-9, mouse

• CAS Number: 686324-96-9
• UNSPSC Description: Chemerin-9, mouse (Chemerin148-156, mouse) is a C-terminal nonapeptide of chemerin. Chemerin-9, mouse is a ligand for ChemR23 (EC50 = 42 nM). Chemerin-9, mouse reduces basal lipolysis in primary mouse white adipocytes(IC50 = 3.3 nM). Chemerin-9, mouse enhances memory and relieves Aβ1-42-induced memory impairment in AD mice. Chemerin-9, mouse also inhibits atherogenesis[1][2][3].
• Target Antigen: Chemerin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/chemerin-9-mouse.html
• Solubility: 10 mM in DMSO
• Smiles: N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N[C@@H](CO)C(O)=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O
• Molecular Weight: 1013.15
• References & Citations: [1]Shimamura K, et al. Identification of a stable chemerin analog with potent activity toward ChemR23. Peptides. 2009 Aug;30(8):1529-38.|[2]Lei Z, et al. Chemerin-9 Peptide Enhances Memory and Ameliorates Aβ1-42-Induced Object Memory Impairment in Mice. Biol Pharm Bull. 2020 Feb 1;43(2):272-283.|[3]Sato K, et al. Chemerin-9, a potent agonist of chemerin receptor (ChemR23), prevents atherogenesis. Clin Sci (Lond). 2019 Aug 20;133(16):1779-1796.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported