8-Hydroxyquinoline (Standard)

• Description:

  8-Hydroxyquinoline (Standard) is the analytical standard of 8-Hydroxyquinoline. This product is intended for research and analytical applications. 8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice[1][2][3][4][5].

• Product Name Alternative:

  8-Quinolinol (Standard)

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/8-hydroxyquinoline-standard.html

• Smiles:

  OC1=C2N=CC=CC2=CC=C1

• Molecular Formula:

  C9H7NO

• Molecular Weight:

  145.16

• References & Citations:

  [1]Lawung R, et.al. Repositioning of 8-hydroxyquinoline derivatives as a new promising candidate for combating multidrug resistant Neisseria gonorrhoeae. EXCLI J. 2018 Aug 23;17:840-846. |[2]8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells. J Biol Inorg Chem. 2010 Feb;15 (2) :259-69. |[3]Zhai S, et.al. Tumor cellular proteasome inhibition and growth suppression by |[4]Hamoud MA, et.al. Effects of quinoline and 8-hydroxyquinoline on mouse bone marrow erythrocytes as measured by the micronucleus assay. Teratog Carcinog Mutagen. 1989;9 (2) :111-8. |[5]Searle CE. The selective depigmenting action of 8-hydroxyquinoline on hair growth in the mouse. Br J Dermatol. 1972 May;86 (5) :472-80.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [148-24-3]