Nortriptyline-d3 (hydrochloride)

Nortriptyline-d3 (hydrochloride)

• CAS Number: 203784-52-5
• UNSPSC Description: Nortriptyline-d3 (hydrochloride) is the deuterium labeled Nortriptyline hydrochloride. Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression[1].
• Target Antigen: Apoptosis; Autophagy; Drug Metabolite; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Apoptosis;Autophagy;Metabolic Enzyme/Protease;Others
• Applications: Cancer-programmed cell death
• Field of Research: Neurological Disease; Cancer
• Purity: 99.75
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: C(CCNC([2H])([2H])[2H])=C1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
• Molecular Weight: 302.86
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported