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Eicosapentaenoic acid ethyl ester

CAT: 0804-HY-B0747-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0747-01Size:50 mg
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Description
Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats[1][2][3].
CAS Number
86227-47-6
Product Name Alternative
EPA ethyl ester; Ethyl eicosapentaenoate; AMR101
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Eicosapentaenoic-acid-ethyl-ester.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)
Smiles
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(OCC)=O
Molecular Formula
C22H34O2
Molecular Weight
330.50
Precautions
H302, H315, H319, H335
References & Citations
[1]Jacobson TA. A new pure ω-3 eicosapentaenoic acid ethyl ester (AMR101) for the management of hypertriglyceridemia: the MARINE trial. Expert Rev Cardiovasc Ther. 2012 Jun;10 (6) :687-695.|[2]Makino M, et al. Effect of eicosapentaenoic acid ethyl ester on hypothyroid function. J Endocrinol. 2001 Nov;171 (2) :259-65.|[3]Pérez-Echarri N, et al. Down-regulation in muscle and liver lipogenic genes: EPA ethyl ester treatment in lean and overweight (high-fat-fed) rats. J Nutr Biochem. 2009 Sep;20 (9) :705-14.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Human Endogenous Metabolite