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C-Kit-IN-7

CAT: 0804-HY-168580Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168580Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C-Kit-IN-7 (Compound 104) is a potent inhibitor of c-Kit, with IC50 values of ≤10 nM. c-Kit-IN-7 inhibits the cell proliferation in GIST430 and BaF3 mutants, with IC50 values of ≤100 nM. c-Kit-IN-7 plays an important role in cancer driven by c-KIT kinase mutations research[1].
CAS Number
2941026-35-1
UNSPSC
12352211
Target
C-Kit
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-kit-in-7.html
Smiles
CC(C#N)(CCNC(NC1=CC=C(C=C1)NC2=NC=NC3=CC(OCCN4CCOCC4)=CC(F)=C32)=O)C
Molecular Formula
C27H32FN7O3
Molecular Weight
521.59
References & Citations
[1]Deciphera Pharmaceuticals, LLC. Preparation of heterocyclic compounds as KIT kinase inhibitors. World Intellectual Property Organization, WO2023107863 A1 2023-06-15
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported