CNST rabbit pAb

CAT: 0855-ES17345-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES17345-01Size:50 µL

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Background

Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]) .[supplied by OMIM, Jun 2010]

Description

Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al. 2010 [PubMed 19864490]). [supplied by OMIM, Jun 2010],

UniProt

Q6PJW8

Swiss Prot

Q6PJW8

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human CNST AA range: 296-346

Target

CNST

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle . Located predominantly in the trans-Golgi network. Probably trafficks between the trans-Golgi network and the cell membrane via the secretory pathway.

Gene ID (Human)

163882

UniProtKB · Q6PJW8

Consortin

CNST_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q6PJW8
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CNST
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q5VSY9, Q5VTM7, Q8IYA9, Q8N3L5, Q8NB09, Q8TEI2, Q96MR5

Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmic vesicleGolgi apparatusMembrane

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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Alternative Products

Catalog	Name
RA23607-01	CNST rabbit pAb
GTR18403596-01	CNST rabbit pAb Antibody
E10G03349	CNST Rabbit Polyclonal Antibody
NBP3-06530-50ul	Rabbit Polyclonal CNST Antibody
NBP3-06530H	Rabbit Polyclonal CNST Antibody [HRP]
TA370810	Consortin (CNST) Rabbit Polyclonal Antibody
PAV6167	Rabbit Anti-CNST Polyclonal Antibody
NBP3-06530B	Rabbit Polyclonal CNST Antibody [Biotin]
NBP3-06530F	Rabbit Polyclonal CNST Antibody [FITC]
MBS8110421-01	Anti-CNST Antibody, Rabbit Polyclonal