Recombinant Rat CCL2/JE/MCP-1 Protein(Trx Tag)

Recombinant Rat CCL2/JE/MCP-1 Protein(Trx Tag)

• Background: Monocyte chemoattractant protein 1 (CCL2/JE/MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. CCL2/JE/MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of CCL2/JE/MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.
• Abbreviation: CCL2/JE/MCP-1
• Synonyms: CCL, Scya, C-C motif chemokine, Small-inducible cytokine A, Monocyte chemotactic protein, Monocyte chemoattractant protein, GDCF, HSMCR, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, Monocyte chemotactic protein 1, SMC-CF, Ccl2, C-C motif chemokine 2, Small-inducible cytokine A2, Monocyte chemotactic protein 1 (MCP-1), Monocyte chemoattractant protein 1, Immediate-early serum-responsive protein JE, Je, Mcp1, Scya2
• CAS Number: 9000-83-3
• UniProt: P14844
• Accession Number: P14844
• Host: E. coli
• Origin Species: Rat
• Tag: N-Trx
• Sequence: Gln24-Asn148
• Purity: > 90% as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
• Molecular Weight: 30 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.