JE (MCP-1, CCL2) Recombinant Protein

JE (MCP-1, CCL2) Recombinant Protein

• Description: The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
• Synonyms: Ccl2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594
• CAS Number: 9000-83-3
• NCBI Gene ID: 20296
• UniProt: P10148
• Accession Number: NP_035463.1
• Accession Number mRNA: NM_011333.3
• Gene Location: 11 C-E1; 11 46.5 cM
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Human, Mouse, Rabbit, Monkey, Bacteria
• Sequence: QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
• Detection Range: Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 125
• Form: Lyophilized
• Molecular Weight: 13.8 kDa
• Shipping Conditions: Room Temperature