TNKS-2-IN-2

TNKS-2-IN-2

• CAS Number: 2719726-91-5
• UNSPSC Description: TNKS-2-IN-2 is a potent and selective inhibitor of TNKS2 with an IC50 of 22 nM[1].
• Target Antigen: PARP
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/tnks-2-in-2.html
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: COC1=C(C(OC)=CC(C(NC2=CC=C(C=C2)NC(C3=CNC4=CC=CC=C4C3=O)=O)=O)=C1)OC
• Molecular Weight: 473.48
• References & Citations: [1]Zhang X, et al. Design, synthesis, and biological activity evaluation of new tankyrase-2 directed inhibitors. Chem Biol Drug Des. 2023 Oct 10.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported