TNKS-2-IN-1
CAT:
804-HY-23338-02
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TNKS-2-IN-1
- CAS Number: 4765-59-7
- UNSPSC Description: TNKS-2-IN-1 (Compound 13g) is a TNKS-2 inhibitor. TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM[1].
- Target Antigen: PARP
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/tnks-2-in-1.html
- Purity: 95.77
- Solubility: DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C1N=C(C2=CC=C([N+]([O-])=O)C=C2)NC3=C1C=CC=C3
- Molecular Weight: 267.244
- References & Citations: [1]Nathubhai A, et al. Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases. Eur J Med Chem. 2016 Aug 8;118:316-27.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported