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Sinapultide (TFA)

CAT: 0804-HY-P2207ASize: 1 EachDry Ice: NoHazardous: No
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Description
Sinapultide TFA is a 21-amino-acid peptide that mimics the action of human surfactant protein-B (SP-B) . Sinapultide TFA can be used for synthetic phospholipids surfactants improvement[1].
CAS Number
2828433-25-4
UNSPSC
12352209
Hazard Statement
H302-H315-H319-H335
Target
Biochemical Assay Reagents
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sinapultide-tfa.html
Solubility
10 mM in DMSO
Smiles
OC(C(F)(F)F)=O.NCCCC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C128H239F3N26O24
Molecular Weight
2583.42
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Braide-Moncoeur O, et al. Peptide-based synthetic pulmonary surfactant for the treatment of respiratory distress disorders. Curr Opin Chem Biol. 2016 Jun;32:22-8. |[2]Liu D, et al. Sinapultide TFA-Loaded Microbubbles Combined with Ultrasound to Attenuate Lipopolysaccharide-Induced Acute Lung Injury in Mice. Drug Des Devel Ther. 2020 Dec 22;14:5611-5622.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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