RegisterLogin

Pimozide (Standard)

CAT: 0804-HY-12987R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-12987R-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Pimozide (Standard) is the analytical standard of Pimozide. This product is intended for research and analytical applications. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5.
CAS Number
[2062-78-4]
Product Name Alternative
R6238 (Standard)
UNSPSC
12352005
Hazard Statement
H302-H361
Target
Adrenergic Receptor; Dopamine Receptor; Parasite; Reference Standards; STAT
Type
Reference Standards
Related Pathways
Anti-infection; GPCR/G Protein; JAK/STAT Signaling; Neuronal Signaling; Others; Stem Cell/Wnt
Field of Research
Cancer; Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/pimozide-standard.html
Purity
99.81
Smiles
O=C1NC2=CC=CC=C2N1C3CCN(CCCC(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5)CC3
Molecular Formula
C28H29F2N3O
Molecular Weight
461.55
Precautions
P264-P270-P280-P330-P405-P501
References & Citations
[1]Ybema CE, et al. Adrenoceptors and dopamine receptors are not involved in the discriminative stimulus effect of the 5-HT1A receptor agonist flesinoxan. Eur J Pharmacol. 1994 Apr 21;256 (2) :141-7.|[2]Cai N, et al. The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression. Am J Transl Res. 2017 Aug 15;9 (8) :3853-3866. eCollection 2017.|[3]Erik A. Nelson, et al. The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors. Blood. 2011 Mar 24; 117 (12) : 3421-3429.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched

Related Products

CatalogName
HY-12987-01Pimozide
HY-12987SPimozide-d4
HY-W704363-01Pimozide-d5
HY-12987S2-01Pimozide-d4-1
HY-12987S1-01Pimozide-d5 N-Oxide
HY-10882R-01Clotrimazole (Standard)
HY-N7083R-01Citral (Standard)
HY-N6691RVeratridine (Standard)
HY-17515RIpfencarbazone (Standard)
HY-N0037R-01Albiflorin (Standard)

Alternative Products

CatalogName
M13205-01Pimozide
RM-P131606-01Pimozide D4
MBS5767346Pimozide-d4
sc-499666Dehydro Pimozide
A17375-50Pimozide 50mg
TRC-D289865-250MGDesfluoro Pimozide
A17375-100Pimozide 100mg
A17375-25Pimozide 25mg
TRC-P447810-10MGPimozide N-Oxide
sc-499667Dehydro Pimozide-d4

Popular Products