Gallium maltolate

• UNSPSC Description:

  Gallium maltolate (GAM) is an apoptosis inducer with anti-cancer and anti-inflammatory activity. Gallium maltolate (GAM)-induced apoptosis involves the oxidative stress and p53 pathways[1][2].

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Purity:

  99.93

• Solubility:

  H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  CC1=C2[O-][Ga+3]([O-]C3=C4C)([O]=C3C=CO4)([O]=C5C=CO6)([O]=C2C=CO1)[O-]C5=C6C

• Molecular Weight:

  445.03

• References & Citations:

  [1]Xuesong Wu, et al. Gallium maltolate inhibits human cutaneous T-cell lymphoma tumor development in mice. J Invest Dermatol. 2015 Mar;135(3):877-884.|[2]F Sampieri, et al. Efficacy of gallium maltolate against Lawsonia intracellularis infection in a rabbit model. J Vet Pharmacol Ther. 2014 Dec;37(6):571-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  Phase 2

• CAS Number:

  [108560-70-9]