JCP-170

• Description :

  JCP-170, a substituted chloroisocoumarin, is an ABHD6 inhibitor. JCP-170 robustly and reproducibly inhibits metastatic seeding of the murine cell line 0688M and both human pancreatic ductal adenocarcinoma (PDAC) cell lines[1].

• UNSPSC :

  12352005

• Target :

  MAGL

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/jcp-170.html

• Smiles :

  O=C(C(C1=CC=CC=C1)C2=CC=CC=C2)NC3=CC=C(C(Cl)=C(OC4=O)OC)C4=C3

• Molecular Formula :

  C24H18ClNO4

• Molecular Weight :

  419.86

• References & Citations :

  [1]Grüner BM, et al. An in vivo multiplexed small-molecule screening platform. Nat Methods. 2016 Oct;13 (10) :883-889.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [120218-98-6]