BF-170

• Target :

  Microtubule Associated

• Related Pathways :

  Cytoskeletal Signaling

• Bioactivity :

  BF-170 is a selective tau fiber-binding agent with an EC50 of 221 nM. It demonstrates excellent blood-brain barrier penetration, reaching a concentration of 9.1% ID/g in brain tissue 2 minutes after intravenous injection in mice (with a clearance rate of 0.25% ID/g at 30 minutes) . BF-170 can serve as a probe for imaging tau protein pathology in Alzheimer's disease (AD) . It plays a significant role in early-stage Alzheimer's disease studies and holds promise for imaging research in tau-related neurodegenerative diseases.

• Smiles :

  N=1C=2C=CC=CC2C=CC1C=3C=CC(N)=CC3

• Molecular Formula :

  C15H12N2

• Molecular Weight :

  220.269

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  22191-97-5