KDM4-IN-2
CAT:
804-HY-128343-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
KDM4-IN-2
- CAS Number: 2369607-62-3
- UNSPSC Description: KDM4-IN-2 (Compound 19a) is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively[1].
- Target Antigen: Histone Demethylase
- Type: Reference compound
- Related Pathways: Epigenetics
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/kdm4-in-2.html
- Purity: 98.29
- Solubility: DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C1C2=CC=NC(N3C=C(CCN4CCC5(CCC6=C5C=CC=C6)CC4)C=N3)=C2N=CN1
- Molecular Weight: 426.51
- References & Citations: [1]Le Bihan YV, et al. C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. Eur J Med Chem. 2019 Sep 1;177:316-337.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported