Products for Research Use Only
RegisterLogin

KDM4-IN-4

CAT: 0804-HY-150619-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-150619-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KDM4-IN-4 (compound 47) is a potent histone lysine demethylase 4 (KDM4) inhibitor with a modest affinity binding to ~80 μM for KDM4A-Tudor domain. KDM4-IN-4 can inhibit H3K4Me3 binding to the Tudor domain in cells with an EC50 value of 105 μM. KDM4-IN-4 can be used for researching anticancer[1].
CAS Number
2230475-63-3
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kdm4-in-4.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@]2(C3=CC=CC=C3)C[C@H](CC2)[C@@H]1CN(C)C
Molecular Formula
C16H23NO
Molecular Weight
245.36
References & Citations
[1]Wu Q, Young B, Wang Y, Davidoff AM, Rankovic Z, Yang J. Recent Advances with KDM4 Inhibitors and Potential Applications. J Med Chem. 2022 Jul 15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM4

Related Products

CatalogName
HY-132896-01KDM4-IN-3
HY-128343-01KDM4-IN-2
HY-173136KDM4 ligand-1
HY-173135PROTAC KDM4 degrader-1
HY-173137KDM4 Ligand-Linker Conjugate 1
HY-W099255-01Ethyl 4,4,4,4',4',4'-hexafluoro-DL-valinate
HY-W7200064,4'-Diapo-ω, ω-carotene-4,4'-dial
HY-77910-014- (4-Bromophenyl) -4-hydroxypiperidine
HY-W0142264,4'-Dihydroxybenzophenone
HY-N90384',4''-Dihydroxyanigorootin

Alternative Products

CatalogName
T60354-01KDM4-IN-4
BA4808-1KDM4-IN-2
BA4798-10KDM4-IN-3
T27722-01KDM4-IN-I
A18856-100KDM4-IN-2 100mg
A18856-10KDM4-IN-2 10mg
T206819-01KDM4 ligand-1
A18856-50KDM4-IN-2 50mg
A18856-25KDM4-IN-2 25mg
A18856-5KDM4-IN-2 5mg

Popular Products