alpha-Bisabolol
CAT:
804-HY-121222-01
Size:
500 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
alpha-Bisabolol
- CAS Number: 515-69-5
- UNSPSC Description: alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities[1][2].
- Target Antigen: Apoptosis; PI3K
- Type: Natural Products
- Related Pathways: Apoptosis;PI3K/Akt/mTOR
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/alpha-bisabolol.html
- Purity: 80.0
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: C/C(C)=C\CC[C@@](O)([C@@H]1CCC(C)=CC1)C
- Molecular Weight: 222.37
- References & Citations: [1]Wu S, et al. Anticancer effects of α-Bisabolol in human non-small cell lung carcinoma cells are mediated via apoptosis induction, cell cycle arrest, inhibition of cell migration and invasion and upregulation of P13K/AKT signalling pathway. J BUON. 2018 Sep-Oct;23(5):1407-1412.|[2]Nur Elena Zaaba, et al. The Nephroprotective Effects of α-Bisabolol in Cisplatin-Induced Acute Kidney Injury in Mice. Biomedicines. 2022 Apr 3;10(4):842.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported