Ac-YEVD-AMC

Ac-YEVD-AMC

• CAS Number: 1631716-11-4
• UNSPSC Description: Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate[1].
• Target Antigen: Fluorescent Dye
• Type: Peptides
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/ac-yevd-amc.html
• Purity: 99.59
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C1C=C(C2=CC=C(C=C2O1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)CC3=CC=C(O)C=C3)=O)CCC(O)=O)=O)C(C)C)=O)CC(O)=O)=O)C
• Molecular Weight: 723.73
• References & Citations: [1]Havira MS, et al. Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS. Sci Immunol. 2020 Nov 27;5(53):eabc0217.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported