Anabasine (Standard)

CAT: 0804-HY-B1532R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1532R-01Size:5 mg
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Description
Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S) -Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana) . Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs) . Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) [1][2].
CAS Number
[494-52-0]
Product Name Alternative
(S) -Anabasine (Standard) ; (+) -Anabasine (Standard)
UNSPSC
12352005
Target
NAChR; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/anabasine-standard.html
Smiles
C1([C@H]2NCCCC2)=CC=CN=C1
Molecular Formula
C10H14N2
Molecular Weight
162.23
References & Citations
[1]Levin ED, et al. Effects of tobacco smoke constituents, anabasine and anatabine, on memory and attention in female rats. J Psychopharmacol. 2014 Oct;28 (10) :915-22.|[2]Benedict T Green, et al. Actions of piperidine alkaloid teratogens at fetal nicotinic acetylcholine receptors. Neurotoxicol Teratol. May-Jun 2010;32 (3) :383-90.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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