Anabaseine (Standard)

• Description :

  Anabaseine (Standard) is the analytical standard of Anabaseine. This product is intended for research and analytical applications. Anabaseine is a non-selective nicotinic agonist. Anabaseine stimulates all AChRs, preferentially stimulates skeletal muscle and brain α7 subtypes[1][2]. Anabaseine is also a weak partial agonist at α4β2 nAChRs[3].

• UNSPSC :

  12352100

• Target :

  NAChR; Reference Standards

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Field of Research :

  Neurological Disease

• Smiles :

  C1(C2=CC=CN=C2)=NCCCC1

• Molecular Formula :

  C10H12N2

• Molecular Weight :

  160.22

• References & Citations :

  [1]Kem W, et al. The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21) : Chemical and Pharmacological Properties. Mar Drugs. 2006;4 (3) :255-273.|[2]Summers KL et al. Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex. Jpn J Pharmacol. 1997 Jun;74 (2) :139-46.|[3]Andrud K, et al. Investigation of the Possible Pharmacologically Active Forms of the Nicotinic Acetylcholine Receptor Agonist Anabaseine. Mar Drugs. 2019;17 (11) :614. Published 2019 Oct 29.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [3471-05-4]