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Bithionol (sulfoxide)

CAT: 0804-HY-17592A-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-17592A-01Size:10 mM - 1 mL
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Description
Bithionol sulfoxide is an anti-infection agent for parasites. Bithionol sulfoxide has mutagenic activity. Bithionol sulfoxide can be used in the research of parasite infection, such as paragonimiasis, flukes andcestodes infection[1][2][5].
CAS Number
844-26-8
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Bithionol-sulfoxide.html
Concentration
10mM
Purity
99.02
Solubility
DMSO : 233.33 mg/mL (ultrasonic)
Smiles
O=S(C1=CC(Cl)=CC(Cl)=C1O)C2=CC(Cl)=CC(Cl)=C2O
Molecular Formula
C12H6Cl4O3S
Molecular Weight
372.05
References & Citations
[1]Florent RL, et al. In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD) . Dis Aquat Organ. 2010 Sep 17;91 (3) :257-62.|[2]S P Yang, et al. Treatment of paragonimiasis with bithionol and bithionol sulfoxide. Dis Chest. 1967 Aug;52 (2) :220-32. |[3]Lavrič A, et al. Oral toxicity of bithionol sulfoxide in mice and rats. Zbornik Veterinarske Fakultete Univerza Ljubljana 1990 Vol.27 No.1 pp.33-39 ref.22. |[4]Chompoochan T, et al. The anthelmintic effects of bithionol sulfoxide against sheep experimentally infected with Fasciola gigantica[C]//ACIAR PROCEEDINGS. 1996: 189-194. |[5]D.Mourot, et al. Mutagenicity of bithionol sulfoxide and its metabolites in the Salmonella/mammalian microsome test. Mutation Research/Genetic Toxicology, 1987, 188 (1) : 53-55.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Schistosome