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Elafibranor sulfoxide

CAT: 0804-HY-176510-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-176510-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Elafibranor (GFT505) sulfoxide is a sulfoxide metabolite of Elafibranor. Elafibranor is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis[1].
UNSPSC
12352005
Target
Drug Metabolite; PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(OC1=C(C=C(C=C1C)/C=C/C(C2=CC=C(C=C2)S(C)=O)=O)C)(C(O)=O)C
Molecular Formula
C22H24O5S
Molecular Weight
400.49
References & Citations
[1]Ratziu V, et al. Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening. Gastroenterology. 2016 May;150 (5) :1147-1159.e5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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